ELECTRIC PULSES USED IN ELECTROCHEMOTHERAPY AND ELECTROGENE THERAPY DO NOT SIGNIFICANTLY CHANGE THE EXPRESSION PROFILE OF GENES INVOLVED IN THE DEVELOPMENT OF CANCER IN MALIGNANT MELANOMA CELLS

Abstract Background Electroporation is a versatile method for in vitro or in vivo delivery of different molecules into cells.However, no study so far has analysed the effects of electric pulses used in electrochemotherapy (ECT pulses) or electric pulses used in electrogene therapy (EGT pulses) on malignant cells.We studied the effect of ECT and EGT

The evolution of next-generation Internet-of-Things (IoT) in recent years exhibits a unique segment that wireless communication paradigms are oriented towards not only improved spectral efficiency transmission but also energy efficiency.This paper addresses these critical issues by proposing a novel communication model, wilds of eldraine prerelease

Microbial mannanases berness white sneakers are biotechnologically important enzymes since they target the hydrolysis of hemicellulosic polysaccharides of softwood biomass into simple molecules like manno-oligosaccharides and mannose.In this study, we have implemented a strategy of molecular engineering in the yeast Yarrowia lipolytica to improve t

Therapeutic options for managing Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest types of aggressive malignancies, are limited and disappointing.Therefore, despite suboptimal nitrile gloves in a bucket clinical effects, gemcitabine (GEM) remains the first-line chemotherapeutic drug in the clinic for PDAC treatment.The therapeutic limi